Thermo Fisher Scientific CDK7 Monoclonal Antibody (3E3)
CDK7 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 3E3). Western blot, ICC/IF, ELISA, IP 등 다양한 응용에 적합. HeLa 세포를 양성 대조군으로 권장하며, 액상 형태로 -20°C 보관.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2 - 0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 2 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E3 |
| Immunogen | Recombinant human protein purified from E.coli (His/ABD-CDK7 136-346 a.a.) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2538677 |
Product Specific Information
A suggested positive control for this product is HeLa cells.
Target Information
The trimeric complex of CDK7, cyclin H, and MNAT1 functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, involved in transcription initiation and DNA repair. This complex links transcription regulation and the cell cycle. The complex is important for BRCA1-mediated double-strand break repair. CDK7 may be a target of germline cancer-inducing mutations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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