Thermo Fisher Scientific TEF Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to amino acids 200-250 of human TEF if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TEF,uniProtId:Q10587-1,ncbiNodeId:9606,antigenRange:200-250,antigenLength:303,antigenImageFileName:PA5-36187_TEF_Q10587-1_Rabbit.svg,antigenImageFileNamePDP:PA5-36187_TEF_Q10587-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2553406

Product Specific Information

This antibody detects endogenous protein at a molecular weight of 33 kDa.

Purity is >95% by SDS-PAGE.

Target Information

TEF (thyrotrophic embryonic factor), also known as KIAA1655, is a 303 amino acid nuclear transcription factor that belongs to the bZIP (basic region/leucine zipper) family and PAR (proline and acidic amino acid-rich) subfamily. TEF binds DNA as either a homodimer or heterodimer, and is known to transactivate the TSH beta promoter. While broadly expressed in adults, TEF is only found in developing embryonic anterior pituitary gland. TEF accumulates according to a robust circadian rhythm and has also been found to inhibit cell growth by downregulating beta chain expression of cytokine receptors. The functional domains of TEF are highly homologous with other members of the PAR-bZIP subfamily, including albumin D box-binding protein (DABP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.