Thermo Fisher Scientific AMPK gamma-1 Polyclonal Antibody
Rabbit Polyclonal AMPK gamma-1 항체로, 인간 시료에 반응하며 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었고, PBS/glycerol buffer에 보존됩니다. 에너지 대사 조절 연구용으로 사용되며, 연구용으로만 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human AMPK gamma-1. Recombinant protein control fragment (Product #RP-108125) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2662977 |
Product Specific Information
Immunogen sequence:METVISSDSSP AVENEHPQET PESNNSVYT
Highest antigen sequence identity to the following orthologs:
- Mouse: 67%
- Rat: 60%
Target Information
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK).
AMPK is a heterotrimer consisting of an alpha catalytic subunit and non-catalytic beta and gamma subunits.
It functions as a key energy-sensing enzyme that monitors cellular energy status.
Upon activation during metabolic stress, AMPK phosphorylates and inactivates ACC and HMGCR, enzymes involved in fatty acid and cholesterol biosynthesis.
This antibody targets one of the gamma regulatory subunits of AMPK.
Alternatively spliced transcript variants encoding distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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