Thermo Fisher Scientific OAS2 Polyclonal Antibody
OAS2 단백질을 검출하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 및 생쥐 시료에 반응합니다. Western blot과 IHC(파라핀) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 저장용액으로 -20°C에 보관합니다.
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Thermo Fisher Scientific OAS2 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:200–1:1,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to a region derived from internal residues of human 2'-5'-oligoadenylate synthetase 2 (69/71 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635699 |
Product Specific Information
This antibody detects endogenous levels of total OAS2 protein.
Target Information
The OAS2 gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates. These molecules activate latent RNase L, leading to viral RNA degradation and inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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