Thermo Fisher Scientific MYH7 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MYH7 (Myosin-7) protein. Validated for IHC (Paraffin) applications. Detects endogenous total Myosin-7. Supplied as liquid, unconjugated form, purified by antigen affinity chromatography. For research use only.
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- PA550240
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Applications and Tested Dilution
- Application: Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:10–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to residues near the C-terminal of human myosin, heavy chain 7, cardiac muscle, beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635693 |
Product Specific Information
This antibody detects endogenous levels of total Myosin-7 protein.
Target Information
Muscle myosin is a hexameric protein composed of two heavy chains, two alkali light chains, and two regulatory light chains.
The MYH7 gene encodes the beta (slow) heavy chain subunit of cardiac myosin, predominantly expressed in the human ventricle and in slow-twitch skeletal muscle fibers.
Alterations in MYH7 expression are associated with cardiac contractile velocity changes, thyroid hormone depletion, and hemodynamic overload.
Mutations in this gene are linked to familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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