Thermo Fisher Scientific PDCD6 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

This antibody detects endogenous levels of total PDCD6 protein.

Target Information

An increased intracellular Ca²⁺ concentration induces apoptotic cell death. Transiently elevated Ca²⁺ concentrations are required for glucocorticoid-mediated and T cell receptor-mediated pathways, leading to T cell apoptosis. ALG-2 (apoptosis-linked gene 2) is a Ca²⁺-binding protein that participates in regulatory events occurring late in the apoptotic program where several death signals converge. ALG-2 is expressed in normal brain and to a greater extent in ischemic brain. The ALG-2 protein contains five EF-hand-like motifs and shares homology with members of the penta EF-hand family, including Calpain small subunits sorcin and Grancalcin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.