Thermo Fisher Scientific PDCD6 Polyclonal Antibody
PDCD6 단백질을 검출하기 위한 Rabbit Polyclonal 항체로, Western blot과 IHC(Paraffin)에서 사용 가능. Human 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 -20°C 보관. 연구용으로만 사용 가능.
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- PA550249
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to a region derived from internal residues of human programmed cell death 6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2635702 |
Product Specific Information
This antibody detects endogenous levels of total PDCD6 protein.
Target Information
An increased intracellular Ca²⁺ concentration induces apoptotic cell death. Transiently elevated Ca²⁺ concentrations are required for glucocorticoid-mediated and T cell receptor-mediated pathways, leading to T cell apoptosis. ALG-2 (apoptosis-linked gene 2) is a Ca²⁺-binding protein that participates in regulatory events occurring late in the apoptotic program where several death signals converge. ALG-2 is expressed in normal brain and to a greater extent in ischemic brain. The ALG-2 protein contains five EF-hand-like motifs and shares homology with members of the penta EF-hand family, including Calpain small subunits sorcin and Grancalcin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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