
Thermo Fisher Scientific PTP1B Polyclonal Antibody
PTP1B 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC/IF 등에 사용 가능. Human, Mouse, Rat 반응. 고순도(>95%) 항원 친화 크로마토그래피 정제. 연구용으로만 사용.
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Thermo Fisher Scientific PTP1B Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human PTPN1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803994 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
PTP1B (PTPN1) is a tyrosine-protein phosphatase that regulates the endoplasmic reticulum unfolded protein response. It mediates dephosphorylation of EIF2AK3/PERK, inactivating its kinase activity. PTP1B also plays roles in CKII- and p60c-src-induced signal transduction cascades, regulates EFNA5-EPHA3 signaling affecting cell reorganization and repulsion, and modulates hepatocyte growth factor receptor signaling via dephosphorylation of MET.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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