Thermo Fisher Scientific SNCA Monoclonal Antibody (OTI2F6), TrueMAB
인간 SNCA(alpha-synuclein)에 특이적인 단클론 항체로 Western blot 및 IHC(Paraffin)에 적합. 정제된 Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능. 파킨슨병 및 알츠하이머병 관련 연구에 활용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SNCA Monoclonal Antibody (OTI2F6), TrueMAB
Applications
Western Blot (WB)
- Tested Dilution: 1:4,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F6 |
| Immunogen | Full length human recombinant protein of human SNCA produced in HEK293T cell. Target family: alpha Synuclein (UniProt ID: P37840-1), NCBI Node ID: 9606, Antigen range: 1-140 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Alpha-synuclein is a member of the synuclein family, including beta- and gamma-synuclein. These proteins are abundant in the brain and play roles in synaptic transmission and membrane trafficking.
Alpha- and beta-synuclein selectively inhibit phospholipase D2, suggesting involvement in signaling pathways.
Defects in the SNCA gene are linked to Parkinson’s disease pathogenesis.
Alpha-synuclein peptides are major components of amyloid plaques in Alzheimer’s disease brains.
Multiple alternatively spliced transcripts encoding different isoforms have been identified.
Diseases associated with SNCA include Parkinson Disease 1 (Autosomal Dominant) and Dementia, Lewy Body.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.