Thermo Fisher Scientific TYMP Monoclonal Antibody (OTI1H10), TrueMAB
TYMP 단백질을 인식하는 Mouse Monoclonal 항체로 Western Blot 및 IHC(Paraffin)에 적합합니다. Human 시료에 반응하며, Lyophilized 형태로 제공됩니다. 재구성 후 1 mg/mL 농도로 사용 가능하며, 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 311–482 of human TYMP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
TYMP (Thymidine Phosphorylase), also known as PD-ECGF (Platelet-Derived Endothelial Cell Growth Factor) or Gliostatin, catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine into their corresponding bases and 2-deoxyribose-1-phosphate.
It functions as a chemotactic and mitogenic factor for endothelial cells and acts as a non-heparin-binding angiogenic factor in platelets. TYMP is also involved in the activation of fluoropyrimidine-based cytotoxic drugs used in cancer therapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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