Thermo Fisher Scientific CNR2 Recombinant Rabbit Monoclonal Antibody (13H43L20)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

View 1 publication 1 publication

Immunohistochemistry (IHC)

1:500

-

Immunocytochemistry (ICC/IF)

1:500

-

Product Specifications

Species Reactivity

Human, Mouse

Published species

Mouse

Host/Isotype

Rabbit / IgG

Expression System

Expi293

Class

Recombinant Monoclonal

Type

Antibody

Clone

13H43L20

Immunogen

Peptides corresponding to human CNR2 [1) aa341-aa360, 2) aa5-aa25, 3) aa2-25] if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CNR2,uniProtId:P34972-1,ncbiNodeId:9606,antigenRange:2-25|5-25|341-360,antigenLength:360,antigenImageFileName:703485_CNR2_P34972-1_Rabbit.svg,antigenImageFileNamePDP:703485_CNR2_P34972-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2895879

Product Specific Information

This antibody is predicted to react with Rat, Bovine.

Target Information

Cannabinoids exert their well known physiological effects through two G protein coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both cannabinoid receptors have been shown to inhibit adenylyl cyclase as well as stimulate the mitogen-activated protein kinase, MAPK. CB1 receptors also modulate ion channels through direct G-protein interactions. Delta 9-tetrahydrocannibinol and related ligands likely exert their psychoactive effects by inhibiting presynaptic N- and P/Q type calcium channels. CB2 is thought to function primarily in the immune system although it has been suggested to be present in the central nervous system, including the retina.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.