Thermo Fisher Scientific HACE1 Monoclonal Antibody (8D3), FITC
HACE1 단백질을 인식하는 FITC 결합 마우스 단클론 항체로, Human 시료에 반응합니다. WB, IHC(P), ELISA 등 다양한 응용에 적합하며, 단백질 G 정제 및 BSA 함유 PBS 용액 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific HACE1 Monoclonal Antibody (8D3), FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8D3 |
| Immunogen | Mouse monoclonal antibodies raised against His-tagged recombinant full length Human HACE1 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539093 |
Additional Formats
- Unconjugated (MA5-17701)
- Biotin (MA5-17702)
- Custom conjugation available upon request
Product Specific Information
MA5-17703 targets HACE1 in ELISA, IF, IHC (P), and WB applications and shows reactivity with Human samples.
The immunogen is a His-tagged recombinant full-length Human HACE1 protein used to raise mouse monoclonal antibodies.
Target Information
HACE1 is an E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. It regulates Golgi membrane dynamics during the cell cycle by interacting with Rab proteins and mediating ubiquitination during mitotic Golgi disassembly and reassembly. HACE1 also ubiquitinates active RAC1, promoting its degradation and contributing to host defense mechanisms. Additionally, it may function as a transcription regulator through interaction with RARB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.