Thermo Fisher Scientific BAIAP2 Monoclonal Antibody (OTI8G8), TrueMAB

Applications and Tested Dilutions

Product Specifications

Target Information

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane-bound G-proteins to cytoplasmic effector proteins. It functions as an insulin receptor tyrosine kinase substrate, suggesting a role for insulin in the central nervous system. The protein associates with a downstream effector of Rho small G proteins, involved in stress fiber and cytokinesis formation. It plays a role in lamellipodia and filopodia formation in motile cells and may influence neuronal growth-cone guidance. It also interacts with the dentatorubral-pallidoluysian atrophy gene, linked to an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.