Thermo Fisher Scientific PDE1B Monoclonal Antibody (OTI6E4), TrueMAB
PDE1B 단백질을 인식하는 Mouse monoclonal antibody로, WB, IHC, ICC, Flow Cytometry에 사용 가능. Human 시료에 반응하며, 액상 형태로 1 mg/mL 농도. Affinity chromatography로 정제되어 안정적인 신뢰성 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E4 |
| Immunogen | Full length human recombinant protein of human PDE1B produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by the PDE1B gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, specifically the PDE1 subfamily. Members of this family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. PDE1B has dual specificity for the second messengers cAMP and cGMP, with a preference for cGMP as a substrate. These molecules function as key regulators of many physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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