Thermo Fisher Scientific TLX Polyclonal Antibody
TLX 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간 및 다양한 종에 반응성을 보입니다. IHC(P)에서 5.5 µg/mL로 검증되었으며, 항원 친화 크로마토그래피로 정제된 액상 시약입니다. 신경계 및 망막 발달 연구용으로 적합합니다.
- 카탈로그번호
- PA534003
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Bovine, Dog, Horse, Human, Non-human primate, Pig, Rabbit |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from N-terminal extracellular domain of human NR2E1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551366 |
Target Information
Nuclear receptor TLX (NR2E1) is a hepatocyte NF4-like receptor involved in anterior brain differentiation, retinal development, and vision. TLX regulates genes such as RAR beta2 and Pax2 during retinal development. Homozygous TLX mutant mice show reduced forebrain development and increased aggression. Deletion of the TLX locus results in cerebral hypoplasia, blindness, and extreme aggression (fierce phenotype). TLX expression has been documented in mouse brain and eye, and ESTs have been isolated from normal human brain libraries.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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