
Thermo Fisher Scientific VSNL1 Monoclonal Antibody (OTI5C8), TrueMAB
VSNL1 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화됨. 인간 시료 반응성 확인됨. 동결건조 형태로 공급되며, 재구성 후 약 1 mg/mL 농도로 사용 가능. 연구용으로 세포 내 칼슘 신호 조절 연구에 적합.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 2–191 of human VSNL1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The VSNL1 gene encodes a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The protein is strongly expressed in cerebellar granule cells, where it associates with membranes in a calcium-dependent manner. It modulates intracellular signaling pathways in the central nervous system by regulating adenylyl cyclase activity directly or indirectly. Alternatively spliced transcript variants have been observed, though their full-length forms have not been fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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