Thermo Fisher Scientific Transferrin Chimeric Recombinant Rabbit Monoclonal Antibody (TW4.20)
인간 Transferrin의 N-말단 도메인을 인식하는 항체로, Western blot, ICC/IF, Flow cytometry, ELISA 등 다양한 분석에 적합합니다. HEK293 세포에서 발현된 재조합 Rabbit IgG 항체이며, 높은 특이성과 안정성을 제공합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | Assay-dependent |
| Inhibition Assays (IA) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | TW4.20 |
| Immunogen | Iron-free purified human transferrin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074478 |
Product Specific Information
Specificity: Binds to the N-terminal domain of human transferrin.
Target Information
Transferrins (Tf) are approximately 80 kDa blood plasma glycoproteins synthesized by the liver. They are iron-binding transport proteins capable of binding two Fe(3+) ions along with an anion, usually bicarbonate. Transferrin transports iron from absorption and heme degradation sites to storage and utilization sites. Under normal conditions, about one-third of total blood transferrin contains bound iron. Measurement of transferrin levels can indicate blood iron-carrying capacity and abnormalities such as anemia, iron overload, and haemochromatosis. Serum transferrin may also play a role in stimulating cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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