Thermo Fisher Scientific LXR beta Polyclonal Antibody
LXR beta 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, ICC/IF, ChIP 등 다양한 응용에 사용 가능. Human, Mouse, Rat 시료 반응. 항원 친화 크로마토그래피로 정제된 고품질 항체.
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Thermo Fisher Scientific LXR beta Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 3 publications |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View publications |
| ChIP assay (ChIP) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues R(113) Y A C R G S G T C Q M D A(126) of rat LXR beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2154770 |
Product Specific Information
PA1-333 detects LXR beta in human, rat, and mouse samples.
It has been successfully used in Western blot and IF procedures.
By Western blot, this antibody detects an approximately 51 kDa protein representing LXR beta in rat and mouse liver samples.
The immunogen is a synthetic peptide corresponding to residues R(113) Y A C R G S G T C Q M D A(126) of rat LXR beta.
The immunizing peptide (Cat. # PEP-271) is available for use in neutralization and control experiments.
Target Information
The liver X receptors, LXRA and LXRB, form a subfamily of the nuclear receptor superfamily and regulate macrophage function, lipid homeostasis, and inflammation.
LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed.
Ligand-activated LXRs form heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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