Thermo Fisher Scientific MUC16 Monoclonal Antibody (OTI3B6), TrueMAB
인간 MUC16(CA125) 단백질을 표적하는 Mouse IgG2b 단클론 항체로, Western blot 및 IHC(P) 적용에 적합합니다. 고순도 친화 크로마토그래피 정제, 무보존제, 동결건조 형태로 제공되며 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:1,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B6 |
| Immunogen | Human recombinant protein fragment (aa 10329–10628 of human MUC16, produced in E. coli) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of ~1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CA125 determinant is present on a high molecular weight mucin-like glycoprotein. It is expressed in:
- Amnion and derivatives of coelomic and mullerian epithelium (pleura, pericardium, peritoneum)
- Adult tissues: epithelial cells of fallopian tube, endometrium, endocervix, pancreas, colon, gall bladder, stomach, kidney, apocrine sweat gland, and mammary gland
- Mesothelial cell lining of pleura, pericardium, and peritoneum
- Ovarian tumors of serous, endometrioid, or clear cell types and adenocarcinomas of mullerian type
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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