Thermo Fisher Scientific CD20 Monoclonal Antibody (2H7), APC
인간 및 붉은털원숭이 시료에 반응하는 CD20 단클론 항체(APC 결합형). 유세포분석(Flow Cytometry)에 적합하며, 2H7 클론 기반. 단백질 A 정제, 동결건조 형태로 제공되며 4°C 보관. 연구용으로만 사용 가능.
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Applications
- Flow Cytometry (Flow)
- Tested Dilution: Neat
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rhesus monkey |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2H7 |
| Immunogen | Proprietary Immunogen |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Lyophilized |
| Concentration | Not determined |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 1% BSA, 5% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_927855 |
Available Formats
Product Specific Information
- Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4°C.
- For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
- Mouse anti-Human CD20 antibody, clone 2H7 recognizes the human CD20 cell surface antigen, a 33–37 kDa non-glycosylated phosphoprotein.
Target Information
CD20 is a non-glycosylated surface phosphoprotein (33–37 kDa) expressed on mature and most malignant B cells, a subpopulation of T lymphocytes, and follicular dendritic cells.
It regulates transmembrane calcium conductance, cell cycle progression, and B-cell proliferation.
CD20 is associated with lipid rafts, and its expression is synchronous with surface IgM.
After receptor ligation, CD20 remains on the cell surface while BCR undergoes endocytosis.
CD20 is a key target for antibody-mediated therapeutic depletion of B cells in various malignancies.
Diseases linked to CD20 dysfunction include Ms4a1-related common variable immune deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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