Thermo Fisher Scientific MVK Polyclonal Antibody
Human MVK 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot과 ELISA에 사용 가능. Affinity Chromatography로 정제되었으며 PBS/glycerol buffer에 보관. 세포질 내 MVK 단백질 검출에 적합한 연구용 항체.
- 카탈로그번호
- PA592415
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 40–300 of human MVK (NP_000422.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.72 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806484 |
Product Specific Information
Immunogen sequence:
RLQPHSNGKV DLSLPNIGIK RAWDVARLQS LDTSFLEQGD VTTPTSEQVE KLKEVAGLPD DCAVTERLAV LAFLYLYLSI CRKQRALPSL DIVVWSELPP GAGLGSSAAY SVCLAAALLT VCEEIPNPLK DGDCVNRWTK EDLELINKWA FQGERMIHGN PSGVDNAVST WGGALRYHQG KISSLKRSPA LQILLTNTKV PRNTRALVAG VRNRLLKFPE IVAPLLTSID AISLECERVL GEMGEAPAPE QYLVLEELID M
Positive Samples: Raji, BT-474
Cellular Location: Cytoplasm
Target Information
Mevalonate kinase (MVK) is an early enzyme in isoprenoid and sterol synthesis. It catalyzes the ATP-dependent phosphorylation of mevalonic acid to form mevalonate 5-phosphate. Deficiency in MVK activity contributes to mevalonic aciduria and hyperimmunoglobulinemia D/periodic fever syndrome (HIDS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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