Thermo Fisher Scientific MBP Polyclonal Antibody
MBP 단백질을 표적으로 하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. WB, IHC, ICC 등 다양한 응용에 사용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 안정적인 저장 조건을 지원.
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Applications
Western Blot (WB)
- Tested Dilution: 1:5,000–1:10,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:2,000–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Pig, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Purified myelin basic protein isolated from bovine brain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 5 mM sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2942818 |
Target Information
The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. MBP-related transcripts are also present in the bone marrow and immune system, arising from the long MBP gene (Golli-MBP) that contains three additional upstream exons. Alternative splicing from Golli and MBP transcription start sites yields two sets of MBP-related transcripts and gene products.
Golli mRNAs encode hybrid proteins combining N-terminal Golli sequences with MBP sequences, while MBP-only transcripts produce the well-characterized myelin basic proteins. This conserved gene structure suggests that MBP and Golli transcription units are functionally and regulatory interlinked.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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