Thermo Fisher Scientific PEX5 Monoclonal Antibody (OTI6E9)
PEX5 단백질을 인식하는 마우스 단일클론 항체로, Western blot, ICC/IF, Flow Cytometry에 적합합니다. 인간, 개, 설치류 등 다양한 종에 반응하며, 액상 형태로 제공됩니다. Affinity Chromatography로 정제되어 높은 특이성과 재현성을 제공합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Non-human primate, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E9 |
| Immunogen | Full length human recombinant protein of PEX5 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.57 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724995 |
Target Information
The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins essential for the assembly of functional peroxisomes. Peroxisome biogenesis disorders (PBDs) are genetically heterogeneous autosomal recessive diseases characterized by multiple defects in peroxisome function. Although clinical features vary, all PBD patient cells exhibit defects in the import of one or more classes of peroxisomal matrix proteins. Defects in this gene are associated with neonatal adrenoleukodystrophy (NALD), Zellweger syndrome (ZWS), and infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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