Thermo Fisher Scientific IQGAP1 Monoclonal Antibody (OTI6E10), TrueMAB
IQGAP1 단백질을 표적하는 모노클로날 항체로, Western blot 및 IHC(P) 실험에 적합. Human, Mouse, Rat 반응성. Lyophilized 형태로 보존하며, 재구성 시 1 mg/mL 농도 유지. 연구용으로 세포 형태 및 이동성 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 464–609 of human IQGAP1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
IQGAP1 encodes a member of the IQGAP family.
The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain, and one WW domain.
It interacts with cytoskeletal components, cell adhesion molecules, and signaling molecules to regulate cell morphology and motility.
Expression is upregulated by gene amplification in certain gastric cancer cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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