Thermo Fisher Scientific RPS6KA2 Monoclonal Antibody (OTI2D4), TrueMAB
RPS6KA2 단백질을 인식하는 단클론 항체로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat에 반응하며, E.coli에서 발현한 재조합 단백질을 면역원으로 사용했습니다. 동결건조 형태로 제공되며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–51 of human RPS6KA2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
RPS6KA2 (RSK3) serine/threonine kinase is a member of the ribosomal S6 kinase (RSK) family and acts as a signal-transducing intermediate in the cellular response to various growth factors. It is expressed in many tissues, with higher levels in lung and skeletal muscle.
The p90 ribosomal S6 kinases (RSK1–4) function downstream of the ERK/MAPK cascade. Loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, characterized by mental retardation and growth deficits, and may influence G-protein coupled signaling regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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