Thermo Fisher Scientific TLR2 Monoclonal Antibody (TLR2.45), FITC
인간 TLR2 단백질을 인식하는 FITC 결합 단일클론 항체로, ICC/IF, Flow Cytometry, Immunoprecipitation에 사용 가능. 단백질 G 정제, PBS + 1% BSA 보존, 4°C 암소 보관. 면역반응 및 병원체 인식 연구에 적합.
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Thermo Fisher Scientific TLR2 Monoclonal Antibody (TLR2.45), FITC
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunocytochemistry (ICC/IF) | 1:50 | View 1 publication |
| Flow Cytometry (Flow) | 1:50 | - |
| Immunoprecipitation (IP) | 1:50 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TLR2.45 |
| Immunogen | Human Flag-tagged TLR2 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1961045 |
Additional Formats
Product Specific Information
MA1-40320 detects TLR2 from human samples.
MA1-40320 has been successfully used in immunofluorescence, immunoprecipitation, and flow cytometry applications.
The MA1-40320 immunogen is proprietary.
Target Information
TLR2 is a member of the Toll-like receptor (TLR) family, playing a key role in pathogen recognition and activation of innate immunity.
TLR2 forms heterodimers with TLR1 or TLR6 to recognize various bacterial and mycoplasma lipoproteins.
It is highly conserved from Drosophila to humans and expressed abundantly in peripheral blood leukocytes.
TLR2 mediates host responses to Gram-positive bacteria and yeast through NF-kappaB activation.
Expression is regulated by immune modifiers such as LPS, GM-CSF, IL-1, IL-10 (upregulation), and IL-4, IFN-gamma, TNF (downregulation).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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