Thermo Fisher Scientific Factor X/Xa (Calcium-dependent) Monoclonal Antibody (CaFX-50), Biotin
Human Factor X/Xa 특이적 단일클론 항체로, 칼슘 의존적 결합 특성을 가짐. Biotin으로 표지되어 ELISA 및 Western blot에 적합. 고순도 정제된 항체로 안정적 저장 가능. 연구용 혈액응고 인자 분석에 활용.
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Thermo Fisher Scientific Factor X/Xa (Calcium-dependent) Monoclonal Antibody (CaFX-50), Biotin
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| ELISA | 0.13 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CaFX-50 |
| Immunogen | Human Factor X purified from the supernatant of thrombin activated platelets |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539034 |
Additional Formats
Product Specific Information
This antibody is specific for Human Platelet Factors X and Xa in the presence of 5–10 mM CaCl₂.
Target Information
Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by excision of the tripeptide RKR. The two chains are held together by disulfide bonds; the light chain contains two EGF-like domains, while the heavy chain contains the catalytic domain homologous to other hemostatic serine proteases. The mature factor is activated by cleavage of the activation peptide by factor IXa (intrinsic pathway) or factor VIIa (extrinsic pathway). Activated Factor X converts prothrombin to thrombin in the presence of factor Va, Ca²⁺, and phospholipid during blood clotting. Mutations can lead to Factor X deficiency, a hemorrhagic condition of variable severity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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