Thermo Fisher Scientific DCI Polyclonal Antibody
Rabbit polyclonal antibody against human ECI1 (DCI) for WB and IHC applications. Detects endogenous ECI1 protein involved in fatty acid β-oxidation. Supplied as liquid, unconjugated, purified by affinity chromatography, stored at -20°C.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ECI1 (Accession P42126), corresponding to amino acid residues A39–K89 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851794 |
Product Specific Information
Antibody detects endogenous levels of total ECI1.
Target Information
Protein Names:
Enoyl-CoA delta isomerase 1, mitochondrial; 3,2-trans-enoyl-CoA isomerase; Delta(3),Delta(2)-enoyl-CoA isomerase; Dodecenoyl-CoA isomerase (Short name: D3,D2-enoyl-CoA isomerase)
Gene Names:
ECI1, DCI
Function:
Isomerizes both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species.
Catalytic Activity:
(3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA
Pathway:
Lipid metabolism; fatty acid β-oxidation
Subunit Structure:
Homotrimer
Subcellular Location:
Mitochondrion matrix
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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