Thermo Fisher Scientific ITPA Polyclonal Antibody
ITPA 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합. Human, Mouse, Rat 시료 반응성. Affinity chromatography로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ITPA (Accession Q9BY32), corresponding to amino acid residues R130–R180 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851798 |
Product Specific Information
Antibody detects endogenous levels of total ITPA.
Target Information
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP), as well as 2′-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5′-triphosphate (XTP) to their respective monophosphate derivatives.
The enzyme does not distinguish between the deoxy- and ribose forms. It likely excludes non-canonical purines from RNA and DNA precursor pools, preventing their incorporation into nucleic acids and avoiding chromosomal lesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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