Thermo Fisher Scientific 5HT7 Receptor/HTR7 (extracellular) Polyclonal Antibody
5HT7 수용체(HTR7)의 세포외 영역을 인식하는 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 반응성. Western blot, IHC(F), Flow cytometry에 사용 가능. 항원 친화 크로마토그래피로 정제된 비결합 항체. -20°C 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:300 |
| Flow Cytometry (Flow) | 5 µg |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CGEQINYGRVEK (aa 73–84 of rat 5-HT7, extracellular N-terminus) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 25 µL, 50 µL, or 0.2 mL of double distilled water (DDW), depending on sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution: Store at 4°C, protected from light, for up to 1 week.
For longer storage, aliquot and keep at -20°C. Avoid repeated freeze/thaw cycles.
Centrifuge antibody preparations before use (10,000 × g, 5 min).
Target Information
5-HT7 Receptor is a serotonin receptor involved in:
- Regulation of circadian rhythm
- Smooth-muscle relaxation in vasculature and GI tract
It has been implicated in depression, autism, and other neuropsychiatric disorders.
Three isoforms have been documented:
- Isoform a: 445 aa
- Isoform b: 432 aa
- Isoform d: 479 aa
Expression reported in aorta, brain, heart, placenta, small intestine, spleen, artery, and vessel.
An EST has been isolated from a testis library.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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