Thermo Fisher Scientific 5HT5B Receptor (HTR5B) (extracellular) Polyclonal Antibody

Applications

• Western Blot (WB): Tested dilution 1:400

Product Specifications

Product Specific Information

Reconstitution: Add 25 µL, 50 µL, or 0.2 mL of double distilled water (DDW) depending on sample size. The antibody ships lyophilized at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C, protected from light, for up to 1 week. For long-term storage, aliquot and keep at -20°C. Avoid multiple freeze/thaw cycles.
Centrifuge antibody preparations before use (10,000 × g, 5 min).

Target Information

SR-5B, also known as 5-hydroxytryptamine (serotonin) receptor 5B (5-HT5B) or G protein-coupled receptor 134 (GPR134), is a receptor for the monoamine ligand serotonin (5-hydroxytryptamine, 5-HT).
Serotonin, a neurotransmitter produced by serotonergic neurons and enterochromaffin cells, influences depression, anxiety, sexuality, and appetite through its receptors.
Rat SR-5B is expressed in serotonergic neurons of the dorsal raphe (DR) and central superior nucleus (CS, median raphe nucleus). DR cell bodies showing SR-5B mRNA expression are abundant in the medial nucleus, and CS coexpression of SR-5B receptor mRNA with serotonin transporter mRNA is high in intermediate portions.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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