
Thermo Fisher Scientific CD14 Polyclonal Antibody
Human CD14 인식 염소 폴리클로날 항체로, Western blot, IHC, Flow cytometry 등에 사용 가능. 0.5 mg/mL 농도의 액상 제품으로 TBS(pH 7.3) 및 BSA 함유. Ammonium sulfate 침전 정제. CD14 관련 면역학 연구용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Internal sequence corresponding to amino acids C-KRVDADADPRQYAD (aa 71–85) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_1071251 |
Product Specific Information
This antibody is tested in Peptide ELISA with an antibody detection limit dilution of 1:128,000.
Target Information
CD14 is a 55 kDa GPI-anchored glycoprotein expressed on the surface of mature monocytes, macrophages, and neutrophils. It functions as a multifunctional lipopolysaccharide receptor and exists in both membrane-bound and soluble forms. CD14 interacts with lipopolysaccharide-binding protein (LBP) to bind lipopolysaccharides and plays a role in neutralizing serum lipopolysaccharides. It also binds apoptotic cells and is involved in allergic, inflammatory, and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. CD14 dysfunction is associated with diseases such as Mycobacterium chelonae infection and Croup.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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