Thermo Fisher Scientific c-Fos Polyclonal Antibody
Western blot, IHC, ICC 등 다양한 응용에 적합한 c-Fos 항체. 사람, 마우스, 랫트 반응성. 정제된 토끼 다클론 항체로 고순도 액상 형태. 세포 신호전달 및 발현 연구용으로 적합.
- 카탈로그번호
- PA5143600
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (IHC) | 1:5,000–1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length recombinant human protein expressed in and purified from E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 5 mM sodium azide |
| Storage Conditions | Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2942829 |
Target Information
FBJ murine osteosarcoma viral oncogene homolog, commonly known as c-Fos, belongs to the Fos transcription factor family and is encoded by the C-FOS gene on chromosome 14.
c-Fos forms a heterodimer with c-Jun to create the Activator Protein-1 (AP-1) transcription factor, which regulates genes involved in signal transduction, cell proliferation, and differentiation.
c-Fos is phosphorylated by various stimuli including growth factors and insulin at multiple sites. The ERK MAPK kinase phosphorylates Threonine 232, regulating nuclear localization and transcriptional activity of c-Fos.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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