Thermo Fisher Scientific Phospho-EZH2 (Thr345) Polyclonal Antibody
EZH2 단백질의 Thr345 위치 인산화를 특이적으로 검출하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC 등 다양한 응용 가능. 고순도 정제 및 안정적 PBS/glycerol 저장 포맷. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EZH2 around the phosphorylation site of Thr345 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899210 |
Product Specific Information
Antibody detects endogenous levels of EZH2 only when phosphorylated at Thr345.
Target Information
EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes involved in maintaining the transcriptional repressive state of genes over successive cell generations.
This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems.
Mutations affecting EZH2 can cause Weaver syndrome (WVS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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