Thermo Fisher Scientific HDAC2 Monoclonal Antibody (OTI7E10), TrueMAB
HDAC2 단백질을 인식하는 Mouse 모노클론 항체로, Western blot과 IHC(Paraffin)에 적합합니다. Human, Mouse, Rat 반응성이 있으며, Lyophilized 형태로 제공됩니다. 재구성 후 1 mg/mL 농도로 사용 가능하며, 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7E10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 415–488 of human HDAC2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
HDAC2 belongs to the histone deacetylase family. These enzymes form large multiprotein complexes responsible for deacetylating lysine residues at the N-terminal regions of histones (H2A, H2B, H3, and H4).
HDAC2 associates with various proteins, including the transcription factor YY1, to form transcriptional repressor complexes. It plays a critical role in transcriptional regulation, cell cycle progression, and developmental processes.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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