Thermo Fisher Scientific KRT16 Monoclonal Antibody (OTI7A4), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:150

Product Specifications

Product Specific Information

• For reconstitution, add 100 µL distilled water to obtain a final concentration of approximately 1 mg/mL.
• For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

KRT16 is a member of the keratin gene family. Keratins are intermediate filament proteins that maintain epithelial cell structural integrity. Type I cytokeratins are acidic proteins arranged in heterotypic pairs, clustered on chromosome 17q12-q21.
KRT16 is coexpressed with keratin 14 in epithelial tissues such as esophagus, tongue, and hair follicles.
Mutations in KRT16 are associated with:

• Type 1 pachyonychia congenita
• Non-epidermolytic palmoplantar keratoderma
• Unilateral palmoplantar verrucous nevus

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.