Thermo Fisher Scientific CYP3A7 Monoclonal Antibody (F19 P2 H2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:250

-

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500

-

Flow Cytometry (Flow)

2 µg / 10^6 cells

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Bovine, Human

Published species

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

F19 P2 H2

Immunogen

Synthetic peptide corresponding to residues E S R D E T V S G A, conjugated to ovalbumin. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CYP3A7,uniProtId:P24462-1,ncbiNodeId:9606,antigenRange:494-503,antigenLength:503,antigenImageFileName:MA3-034_CYP3A7_P24462-1_House_mouse.svg,antigenImageFileNamePDP:MA3-034_CYP3A7_P24462-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2261519

Product Specific Information

MA3-034 detects Cytochrome P450 3A7 from Human samples and bovine liver samples.

MA3-034 has been successfully used in Western blot and Immunohistochemistry (paraffin) applications. By Western blot, this antibody detects a ~54 kDa band representing Cytochrome P450 3A7.

The MA3-034 immunogen is a synthetic peptide corresponding to residues E S R D E T V S G A, conjugated to ovalbumin.

Target Information

This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.