Thermo Fisher Scientific Phospho-EphA4 (Tyr596) Polyclonal Antibody

Thermo Fisher Scientific Phospho-EphA4 (Tyr596) Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:2,000

Species Reactivity

• Human
• Mouse
• Rat

Host / Isotype

• Rabbit / IgG

Class

• Polyclonal

Type

• Antibody

Immunogen

A synthesized peptide derived from human EPHA4 (Accession P54764), corresponding to amino acid residues around phosphorylated Tyr596.

Conjugate

• Unconjugated

Form

• Liquid

Concentration

• 1 mg/mL

Purification

• Sequential chromatography

Storage Buffer

• PBS, pH 7.4, with 50% glycerol

Contains

• 0.02% sodium azide

Storage Conditions

• −20°C

Shipping Conditions

• Wet ice

RRID

• AB_2816591

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Product Specific Information

Antibody detects endogenous levels of EPHA4 only when phosphorylated at Tyr596.

Target Information

EPHA4 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors are involved in developmental processes, particularly within the nervous system.
Receptors in the EPH subfamily typically have:

• A single kinase domain
• An extracellular region containing a cysteine-rich domain and two fibronectin type III repeats

Ephrin receptors are divided into two groups based on extracellular domain sequence similarity and ligand binding affinities (ephrin-A and ephrin-B). EphA4 encodes a protein that binds ephrin-A ligands.

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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.