Thermo Fisher Scientific Phospho-RASGRF1 (Ser927) Polyclonal Antibody
RASGRF1 단백질의 Ser927 인산화 상태를 특이적으로 검출하는 폴리클로날 항체. Western blot 및 IHC(파라핀) 실험에 적합. Rabbit IgG 기반, 액상 형태로 제공되며 PBS/glycerol buffer에 보존. 연구용으로만 사용 가능.
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- PA5105157
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RASGRF1 (Accession Q13972), corresponding to amino acid residues around phosphorylated Ser927 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816630 |
Product Specific Information
This antibody detects endogenous levels of Ras-GRF1 only when phosphorylated at Ser927.
Target Information
RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. It stimulates the dissociation of GDP from RAS protein. Mouse studies indicate that Ras-GEF activity of this protein in the brain can be activated by Ca²⁺ influx, muscarinic receptors, and G protein βγ subunits. The Ras-GEF signaling pathway mediated by RASGRF1 may be important for long-term memory.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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