Thermo Fisher Scientific CDKN2C Monoclonal Antibody (OTI1H1), TrueMAB
CDKN2C 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화되어 있습니다. 인간 유래 시료에 반응하며, 동결건조 형태로 제공됩니다. PBS 버퍼와 트레할로스 포함, 재구성 후 약 1 mg/mL 농도에서 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H1 |
| Immunogen | Full length human recombinant protein of human CDKN2C produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The CDKN2C gene encodes a member of the INK4 family of cyclin-dependent kinase inhibitors.
This protein interacts with CDK4 or CDK6 to prevent activation of CDK kinases, acting as a regulator of cell cycle G1 progression.
Ectopic expression suppresses cell growth in correlation with wild-type RB1 function.
Knockout mouse studies indicate its role in spermatogenesis regulation and tumorigenesis suppression.
Two alternatively spliced transcripts encoding the same protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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