Thermo Fisher Scientific SHP2 Polyclonal Antibody
SHP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합. Human과 Mouse 시료 반응성. 고순도 정제 및 안정적 PBS buffer 보존. 연구용으로만 사용 가능.
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Thermo Fisher Scientific SHP2 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:1,000
- Immunocytochemistry (ICC/IF): 1:10–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein of partial human SHP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ammonium sulfate precipitation, Size-exclusion - Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2284764 |
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules regulating various cellular processes such as growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP includes two tandem Src homology-2 domains that mediate phospho-tyrosine binding and substrate interaction. It is broadly expressed and plays a regulatory role in cell signaling related to mitogenic activation, metabolic control, transcription regulation, and cell migration.
Mutations in this gene are associated with Noonan syndrome and acute myeloid leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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