Thermo Fisher Scientific HAPLN1 Recombinant Rabbit Monoclonal Antibody (6E7)
HAPLN1 단백질을 검출하기 위한 Recombinant Rabbit Monoclonal Antibody(클론 6E7). Western blot, IHC, ICC/IF에 적합하며 높은 특이성과 재현성을 제공. HEK293 발현 시스템에서 생산된 고순도 항체로, 4°C 단기 보관 및 -20°C 장기 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Dog |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6E7 |
| Immunogen | A synthesized peptide derived from human HAPLN1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2717294 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and expressed in HEK293 cells. Individual clones are screened to select the best candidates for production.
Advantages include:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broad immunoreactivity due to the rabbit immune repertoire
Target Information
HAPLN1 belongs to the HAPLN family and contains one Ig-like V-type domain and two Link domains. It stabilizes aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.
Diseases associated with HAPLN1 include:
- Cerebral Creatine Deficiency Syndrome 3
- Rheumatoid Arthritis, Systemic Juvenile
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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