Thermo Fisher Scientific Phospho-GABBR2 (Ser892) Polyclonal Antibody
Phospho-GABBR2 (Ser892)에 특이적인 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 시료에 반응. WB, IHC, ICC, ELISA 등 다양한 응용 가능. Protein A 정제, 1 mg/mL 농도, 안정적인 액상 형태로 -20°C 보관.
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Thermo Fisher Scientific Phospho-GABBR2 (Ser892) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human GABBR2 around the phosphorylation site of Ser892 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The multi-pass membrane protein GABBR2 belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily.
GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, regulating neurotransmitter release, ion channel activity, and adenylyl cyclase.
This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective alone.
Allelic variants of this gene have been associated with nicotine dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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