Thermo Fisher Scientific H2BK16ac Polyclonal Antibody
H2BK16ac에 특이적인 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 시료에 반응합니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합하며, 친화 크로마토그래피로 정제된 액상 형태로 제공됩니다. -20°C 보관, 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human H2BFS (Accession P57053), corresponding to amino acid residues P2–G27 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816576 |
Product Specific Information
Antibody detects endogenous levels of Acetyl-H2B only when acetylated at Lys16.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of the four core histones (H2A, H2B, H3, and H4). These structures further compact DNA into chromatin, regulating accessibility for transcription, replication, and repair. Histones play a central role in transcription regulation, DNA repair, replication, and chromosomal stability. H2B exhibits broad antibacterial activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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