Thermo Fisher Scientific CDw293 Polyclonal Antibody
CDw293 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. WB, IHC, ICC/IF, ELISA에 적합하며 Human, Mouse, Rat 시료에서 반응. 고순도 Affinity Chromatography 정제, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–126 of human BMPR1B (NP_001194.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.49 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914255 |
Product Specific Information
- Positive test controls: 293T, HeLa, SH-SY5Y
- Subcellular location: Membrane, Single-pass type I membrane protein
- Immunogen sequence:
MLLRSAGKLN VGTKKEDGES TAPTPRPKVL RCKCHHHCPE DSVNNICSTD GYCFTMIEED DSGLPVVTSG CLGLEGSDFQ CRDTPIPHQR RSIECCTERN ECNKDLHPTL PPLKNRDFVD GPIHHR
Target Information
BMPR1B (also known as ALK6, CDw293)
BMPR1B is a member of the transmembrane serine/threonine kinase family, part of the bone morphogenetic protein (BMP) receptor group closely related to activin receptors ACVR1 and ACVR2. It plays a key role in endochondral bone formation and embryogenesis. BMPR1B is expressed in normal and cancerous prostate tissues and is relevant in endocrine therapy for prostate cancer. Receptor trafficking of BMPR1B also contributes to FOP pathogenesis and human T-cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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