Thermo Fisher Scientific GSR Monoclonal Antibody (2B3)
GSR 단백질에 특이적인 Thermo Fisher Scientific의 단클론 항체. ELISA 및 IP 실험에 적합하며, HeLa 세포를 양성 대조군으로 권장. 항산화 방어 연구에 활용 가능. 연구용으로만 사용.
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Thermo Fisher Scientific GSR Monoclonal Antibody (2B3)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 1–2 µL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2B3 |
| Immunogen | Purified, recombinant, human glutathione reductase protein expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2115518 |
Product Specific Information
A suggested positive control for this product is HeLa cells.
Target Information
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein and a central component of cellular antioxidant defense. It reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, an important cellular antioxidant.
Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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