Thermo Fisher Scientific ITPKA Polyclonal Antibody
Thermo Fisher Scientific의 ITPKA Polyclonal Antibody는 Mouse 및 Rat 시료에 반응하는 Rabbit IgG 항체입니다. Western blot 및 IHC(Frozen)에 적합하며, 고순도의 항원 친화 크로마토그래피로 정제되었습니다. 세포 내 이노시톨 인산 대사 조절 연구에 활용됩니다.
- 카탈로그번호
- PA585786
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of mouse IP3KA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.78 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792922 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%).
- Positive Control: mouse brain, rat brain.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4.
The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling.
Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.
It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin-dependent protein kinase II, and protein kinase C in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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