
Thermo Fisher Scientific CAV1 Monoclonal Antibody (OTI2C4), TrueMAB
CAV1 단백질을 인식하는 Thermo Fisher Scientific의 단일클론 항체. Western blot 및 IHC(P)에서 검증됨. Human, Mouse, Rat 반응성. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 2–104 of human CAV1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Caveolin-1 (CAV1) is a scaffolding protein within caveolar membranes. It interacts with G-protein alpha subunits and regulates their activity. CAV1 is involved in T-cell receptor-mediated activation, co-stimulatory signaling, and can bind with DPP4 to induce T-cell proliferation and NF-κB activation.
Mutations in the CAV1 gene are associated with congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy with congenital cataracts and neurodegeneration syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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