Thermo Fisher Scientific OCLN Polyclonal Antibody
OCLN 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 Immunoprecipitation에 적합합니다. 인간 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 1 mg/mL 농도이며, 4°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunoprecipitation (IP)
- Tested Amount: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 472–522 of human Occludin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Dog and Orangutan
Target Information
Occludin is a 65 kDa protein that can exist in multiple phosphorylated forms (up to ~82 kDa). It plays a role in regulating localization and function of tight junctions. Polyunsaturated fatty acids up-regulate occludin expression, enhancing transendothelial resistance and reducing permeability. Expression varies by tissue—high in brain tissue at cell-cell contacts, lower and discontinuous in non-neural tissues. Structural features are conserved across species. Under-expression of occludin is linked to increased tumor endothelial permeability and brain tumor edema.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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