Thermo Fisher Scientific TXNL5 Polyclonal Antibody
Human TXNL5 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot과 IHC(Paraffin)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. TNF-α 신호전달 및 산화환원 반응 연구에 적합.
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- PA554639
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TXNL5. Recombinant protein control fragment (Product # RP-93241) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649148 |
Product Specific Information
Immunogen sequence:
MARYEEVSVS GFEEFHRAVE QHNGKTIFAY FTGSKDAGGK SWCPDCVQAE PVVREGLKHI SE
Sequence identity (orthologs):
- Mouse: 76%
- Rat: 73%
Target Information
TXNL5 is a disulfide reductase that may participate in various redox reactions through reversible oxidation of its active center dithiol to a disulfide, catalyzing dithiol–disulfide exchange reactions. It modulates TNF-alpha signaling and NF-kappa-B activation, exhibits peroxidase activity, and may contribute to the elimination of cellular hydrogen peroxide.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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