Thermo Fisher Scientific SCRN2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SCRN2. Recombinant protein control fragment (Product #RP-93285). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SCRN2,uniProtId:Q96FV2-1,ncbiNodeId:9606,antigenRange:195-280,antigenLength:425,antigenImageFileName:PA5-54640_SCRN2_Q96FV2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54640_SCRN2_Q96FV2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647031

Product Specific Information

Immunogen sequence: LSIGTDISAQ HPELRTHAQA KGWWDGQGAF DFAQIFSLTQ QPVRMEAAKA RFQAGRELLR QRQGGITAEV MMGILRDKES GICMDS

Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 80%.

Target Information

SCRN2 is a member of the secernin family of proteins which includes the homologous SCRN1, a protein that was first identified as being involved in the regulation of exocytosis from peritoneal mast cells. Little is known of SCRN2, but studies have shown that SCRN1 may possess epitopes that function as tumor-associated antigens in gastric cancers and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN2 may also be involved in protein secretion or the regulation of cell growth.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.